Generally, the prognosis of nephrotic syndrome caused by microscopic lesion nephropathy and mild thylakoid proliferative glomerulonephritis is better, and there is a possibility of clinical cure. For patients with severely impaired renal function or complications, although they can not be cured after active treatment, their condition can be alleviated. Nephrotic syndrome is a clinical syndrome caused by various kidney diseases. Nephrotic syndrome may be related to genetics, infection, drugs, environment and other factors, and patients may have symptoms such as increased foam in urine, decreased urine output, abdominal distension and weight gain. Patients with nephrotic syndrome can take relevant drugs for treatment under doctor’s guidance, commonly used drugs include prednisone acetate, methylprednisolone, cyclophosphamide and so on. Generally, the prognosis of microscopic lesion nephropathy and mild thylakoid proliferative glomerulonephritis is better after treatment, and there is a possibility of clinical cure, while the prognosis of those with large amount of proteinuria, severe hypertension and renal function damage is worse, and cannot be cured. It is suggested that patients with nephrotic syndrome should pay attention to rest, keep a good attitude, actively cooperate with the doctor’s treatment, strictly comply with the doctor’s instructions for the correct use of medication, do not stop the use of hormone drugs, and regular re-examination, so that the doctor can understand the condition changes in time and adjust the treatment program.