What medication to take for a bitter mouth is generally analyzed based on different causes. Bitter mouth may be due to diabetes, acid reflux, abnormal liver and gallbladder function. 1. Bitter mouth due to diabetes. When the patient suffers from diabetes, there will be endocrine disruption, which causes changes in the oral taste sensation of the bitter mouth, which can be under the guidance of the doctor to take medication to control blood glucose for treatment, such as gliclazide, glimepiride, acarbose, metformin and so on. 2. Bitter mouth may be caused by acid reflux. When the patient’s gastric acid secretion, or the gastric mucosal barrier is damaged, there will be gastric acid reflux, down the esophagus reflux into the mouth, and gastric acid is usually sour and bitter taste, which can be under the guidance of the doctor to take omeprazole, cimetidine, lansoprazole and other drugs to treat. 3. Bitter mouth may be due to abnormal liver and gallbladder function. Abnormalities in liver and gallbladder function can lead to bile overflowing into the mouth, which can lead to a bitter mouth, for which you can take anti-inflammatory choleretic tablets or some hepatoprotective tablets and other medications. Usually pay attention to rest and exercise, wash the mouth more foreign body, and brush your teeth diligently. Do not eat too spicy food, take drugs to follow the doctor’s instructions, not blindly use drugs to avoid adverse reactions.