Small blisters on the hands from heat usually require no special treatment. If the blisters are large in size, medical attention is required. In the hands of high-temperature burns, patients should immediately rinse running water, local ice packs, help relieve swelling, pain and other discomfort. If the blister is small, generally no special treatment, to be absorbed on its own. If the size of the blister is large, you need to cooperate with the doctor in aseptic operation using a syringe to suction the liquid inside the bubble or directly remove the surface of the blister to discharge the liquid inside the bubble. After cooperating with the doctor to deal with the wound, you can also follow the doctor’s instructions to use topical erythromycin ointment, mupirocin ointment and other antibiotics to prevent infection. Localized with severe pain can be prescribed with ibuprofen, acetaminophen and other non-steroidal anti-inflammatory drugs to relieve, if necessary, tetanus antitoxin injection. Daily attention to local skin care, avoid foreign body friction stimulation. It is recommended that the hand is hot blisters follow the doctor’s instructions to use medication, do not use drugs or prescriptions, so as not to aggravate the condition.