The virus is very sensitive to acid, at pH 5.0, it can inactivate 90% of the viability in 1 second, and at pH 5.5 it takes 1 minute to kill more than 90% of the viability, so it can be disinfected with vinegar essence steam. The barn can be disinfected with 2% sodium bicarbonate or 2% potassium hydroxide, 4% sodium carbonate, 1%-2% formaldehyde solution, 30% grass wood ash, 0.2%-5% peroxyacetic acid solution, 5% sodium hypochlorite, 5% ammonia, 0.1% sterilization net solution, etc. All of them are good disinfectants and can be used for disinfection. Foot-and-mouth disease virus is not afraid of drying, and under natural conditions, tissues containing virus or contaminated feed can survive for weeks to months; virus in feces can survive for about 1 month in the warm season.