Lidocaine applied for 10 minutes with no effect may be due to insufficient dosage or too short a duration of application. Epidermal application of lidocaine can block epidermal nerve potential conduction, peripheral nerves can not produce action potential and play the role of analgesia, clinically commonly used in surface anesthesia and gastroscopy. The amount of lidocaine that needs to be applied to the surface of the skin for general surgery is about 1.5~2g/10cm², and if too little is applied, the effectiveness of the drug may be affected. Smear lidocaine on the skin permeability is not particularly good, the effect is slow, usually need 20-30 minutes, local wipe can be used after sealing dressing film, can accelerate the drug absorption, the onset of effect time can be greatly shortened. It is contraindicated for those who are allergic to amide local anesthetics or any other ingredients in this product. If you feel unwell, it is recommended that you consult a doctor promptly.