The following drugs can be used for pain relief treatment of head neuralgia: 1. Drugs specifically for neuralgia, such as pregabalin, gabapentin and carbamazepine, of which carbamazepine is the most effective, but can cause bone marrow suppression, liver function damage, and also often cause dizziness and unstable walking, and are not recommended for the elderly and children. Pregabalin is more expensive, while gabapentin has a slower onset of action, and should be selected according to the patient’s different age, underlying diseases, economic conditions, etc. 2. Non-specific painkillers, which generally refer to non-steroidal anti-inflammatory drugs, such as ibuprofen, naproxen, acetochlorfenac, etc., have relatively weak pain-relieving effects and are generally recommended for temporary use only. 3. Drugs for the cause, if the headache is related to muscle compression, use If the headache is related to tumor compression, surgical treatment should be considered, and drug treatment is ineffective.