What is the cause of high serum cystatin c measurement?

Serum cystatin C is mainly a sensitive indicator to reflect early renal impairment, if cystatin C is high, we should be alert to renal injury.
Serum cystatin C, also known as cysteine protease inhibitor C, is a low molecular weight, alkaline, non-glycosylated protein composed of 120 amino acids.
Elevated serum cystatin C is mainly due to damage to the glomerular filtration membrane, and patients with hypertension, diabetes mellitus and hyperlipidemia are prone to impaired renal function, resulting in elevated serum cystatin C. Patients with acute nephritis and renal insufficiency will also have elevated serum cystatin C values.
A single indicator does not reflect the full picture, it is recommended to further examination, you can choose urine routine, urine micro-protein, 24-hour urine protein quantification, renal ultrasound and so on to comprehensively assess the renal condition.
It is recommended that patients should do timely and comprehensive examination to find out the cause of the disease. Actively cooperate with doctors for treatment to prevent the deterioration of kidney function leading to adverse consequences.