People with severe loss of kidney essence can choose medication, dietary regimen with physical exercise, etc. to regulate. The common causes of severe loss of kidney essence include excessive sexual intercourse, insufficient nutritional intake, and injury to the kidneys caused by prolonged illness, etc. It often manifests itself in mental fatigue, weakness of qi and blood, premature aging, and women’s amenorrhea and infertility; it is possible to take medicines to tonify the kidneys, and at the same time, to regulate the kidneys with diet and physical exercise. Commonly used medicines such as Heche Dazao Pills, Shengjing Pills, Luoyang Jiejing Pills, Liuwei Di Huang Pills, etc. can nourish the kidneys and consolidate the kidney essence (consolidate the kidney essence by nourishing the kidneys) and improve the symptoms of kidney deficiency with low spermatogenesis, etc. On weekdays, one can consume appropriate amount of food such as beef bone marrow, sheep bone, dried scallop, yam and mealybugs which can help to nourish the kidneys and do appropriate exercise such as running, jumping rope, etc. on a daily basis in order to enhance the physical fitness. If the patient has any uncomfortable symptoms, it is recommended to consult a doctor in time, and use medication under the guidance of the physician’s diagnosis, do not self-medication, to avoid causing adverse consequences.