There are many lesions causing right posterior hepatic lobe nodules, which may be either benign proliferative lesions, benign tumors, or malignant tumors. The former mainly includes hepatic focal nodular hyperplasia, hepatic adenoma, and hepatic hemangioma, while the latter mainly includes primary hepatocellular carcinoma and metastatic hepatocellular carcinoma, among which hepatic hemangioma and primary hepatocellular carcinoma are relatively the most common. Hepatic hemangioma is mainly seen in people without previous chronic liver disease, while primary liver cancer is mainly seen in patients with hepatitis B, C and cirrhosis. At present, it is sometimes difficult to distinguish the specific lesion in plain CT, MRI or B-ultrasound, and further clarification is needed through enhanced CT, MRI and tumor markers, and sometimes even through expensive PET-CT and invasive examinations such as liver angiography and liver aspiration biopsy to reach the final diagnosis.