Foaming at the mouth in epileptic seizures is considered to be related to muscle contraction and increased secretion. Epilepsy is caused by abnormal discharges of neurons in the brain, and the muscles of the mouth and throat contract strongly during the onset of epilepsy, resulting in the production of saliva that can’t be swallowed, and at the same time, the patient’s breathing is rapid, which generates a certain amount of airflow, which produces a white foamy secretion. Foaming at the mouth in epilepsy is mostly seen in grand mal epileptic seizures, which are accompanied by tonic spasms of the limbs, impaired consciousness, and clenched teeth. The diagnosis can be confirmed with EEG, cranial MRI or CT examination. When the seizure should be timely medical treatment, under the guidance of the physician to clarify the cause of the disease and then treatment.