A cinchona reaction refers to symptoms such as headache, dizziness, tinnitus, and diarrhea after taking medications related to drugs synthesized from cinchona bark extracts. Commonly used drugs clinically derived from cinchona bark include quinine and quinidine cinchona cream. This class of drugs has the effect of inhibiting and killing the malaria parasite, and at the same time, if overused, it may also suppress the central nervous system. The specific clinical manifestations of cinchona reaction are dizziness, headache, nausea, vomiting, diarrhea, blurred vision and even loss of consciousness in severe cases. Therefore, it is recommended that the drug be used under the guidance of a doctor and should be discontinued promptly if adverse reactions occur.