Large red bumps and hard and itchy considerations may be nodular itchy rash, scabies nodules, as follows: 1, nodular itchy rash: nodules hard texture, usually occurring in the limbs, scratching more serious. Patients can use strong glucocorticoid ointment, such as fluticasone propionate ointment, halometasone ointment coated with treatment, coated and then wrapped in plastic wrap for 20 minutes to play the effect of sealing package treatment, more effective than ordinary topical ointment; 2, scabies nodules: usually in the pubic area, buttocks, hard nodules, in the circumference of the body can be small pimples, especially in the interphalangeal area, navel can be seen in the typical rash performance. Large bumps can be applied with hydrocortisone butyrate ointment, and the small pimples around the body can be treated with Clomid ointment.