There are several reasons for pain in the thumb: First, it may be due to traumatic collision or excessive walking, resulting in a possible fracture or joint, as well as soft tissue strain around the formation of injury or inflammatory lesions, and pain in this location. Secondly, the first metatarsal phalangeal joint may have painful redness and swelling, such as gouty arthritis, which is caused by abnormal purine metabolism, resulting in an increase in uric acid in the human body and the formation of gouty stones in the first metatarsal phalangeal joint, or the accumulation of uric acid salts, which can cause pain in the location. Third, it is due to strenuous exercise, or falling from a high place, the foot steps hard on the ground, resulting in damage to the tendons and ligaments of the sole of the foot, this situation will produce bruising and serious edema, will produce stimulation of the surrounding tissues and peripheral nerves, which will also lead to painful sensations.