Metformin is generally applicable to patients with type 2 diabetes mellitus, and vogliflozin is medically called voglibose, which is generally applicable to patients when they receive dietary therapy or exercise therapy without getting obvious effect, or when they use oral hypoglycemic drugs or insulin preparations in addition to dietary therapy or exercise therapy without getting obvious effect. 1. Metformin: It belongs to the class of biguanide drugs, and is currently mainly used as the first-line drug for type 2 diabetes mellitus, and can be used alone or in combination with other drugs. In addition, for patients with type 1 diabetes mellitus and insulin combined application may reduce insulin dosage and blood glucose fluctuations. 2. Voglibose: belongs to α-glucosidase inhibitor, mainly used for diabetic patients with normal fasting blood glucose (or not too high) and elevated postprandial blood glucose, can be used alone or in combination with other hypoglycemic drugs. In addition, the addition of voglibose to insulin in patients with type 1 diabetes can help reduce postprandial hyperglycemia. Metformin and voglibose need to be used under the guidance of a doctor, it is recommended to consult a medical professional before use and follow the doctor’s instructions.