Foot abrasion blisters need to be picked or extracted from the blisters in a professional institution, and then sterilized locally. Foot blisters are usually caused by long-term walking or inappropriate shoes, mostly seen in outdoor heavy laborers, blisters usually grow on the soles of the feet. The blisters on the soles of the feet should stop walking or laboring, the diameter of the blisters less than half a centimeter can be broken with a hypodermic needle or pronged needle, the diameter of the blisters more than half a centimeter can be extracted with a syringe of the liquid inside. Then use iodophor or alcohol to disinfect the area, after disinfection, you can apply local antiseptic and anti-inflammatory ointment, such as erythromycin ointment or mupirocin ointment. Larger blisters are best wrapped in gauze after extraction. Blisters on the soles of the feet can usually be avoided by suggesting looser shoes and avoiding long periods of walking or standing. Wear socks to reduce friction and shear when wearing leather shoes and high heels.