Interferon and imiquimod are similar in efficacy and can be used instead of imiquimod cream. 1. Interferon has antiviral, immunoregulatory and cell proliferation inhibiting effects, and is suitable for the treatment of malignant tumors, viral skin diseases and certain inflammatory skin diseases. Imiquimod ointment has the effects of immunomodulation, indirect antivirus and inhibition of cell proliferation, both effects are similar, so, interferon can be used instead of imiquimod ointment. 2. Before using interferon, it should be noted that patients with hepatic or renal insufficiency, cardiac insufficiency, allergy to interferon and myelosuppression are prohibited, and some patients may have adverse reactions such as mild itching, burning sensation and tingling sensation on local skin. During the treatment period, it is important to prohibit sexual intercourse and not to use the drug during menstruation. It is recommended that patients under the guidance of a doctor for treatment, do not blindly use their own medication to avoid adverse reactions.