If women around 40 years of age suffer from insomnia, after excluding other causes, they need to consider whether female menopausal syndrome has occurred. The common age of onset is between 45 and 55 years old, but in recent years, the age of onset has an earlier trend, many patients around 40 years old, a series of mental and physical disorders. Patients often inexplicably feel irritable, anxious, easily agitated and easily lose their temper, and cannot control themselves. During the day, they feel that their ability to study and work decreases, and they have trouble concentrating and forgetfulness. At night, insomnia, difficulty in falling asleep, early awakening, dreaming, difficulty in maintaining sleep and other symptoms will appear at the same time. It is recommended to improve the relevant hormone examination, if there is obvious estrogen decompensation, it is recommended to supplement hormone therapy. At the same time for the patient’s anxiety and depression, can also take related drugs. Patients with milder symptoms may consider using proprietary Chinese medicines, such as Tranquilizing Spirit and Brain Tonic Liquid and Female Genuine Granules.