Generalized chills are not necessarily a precursor to myocardial infarction. Whether generalized chills are a precursor of myocardial infarction needs to be determined initially by combining the patient’s medical history and other symptoms. 1. Chest tightness and chest pain: it occurs early in the morning, usually more severe and lasts for a longer time, up to several hours or longer, rest or oral medication is ineffective, and the pain can be radiated to the jaw, neck and upper back. 2. Systemic symptoms: fever, tachycardia, elevated white blood cell count, increased erythrocyte sedimentation rate, and some patients’ body temperature rises to 38℃. 3. Gastrointestinal symptoms: frequent nausea, vomiting, epigastric distension, etc., usually related to vagus nerve stimulation by necrotic myocardium and reduced cardiac output, inadequate tissue perfusion. 4. Arrhythmia: it occurs 1~2 days after the onset of the disease, and is most common within 24 hours, often showing weakness, dizziness, fainting, etc., of which ventricular arrhythmia is more common. In addition, simple generalized chills are related to many factors, such as physiological factors such as the cold external climatic environment, etc. Pathological factors such as upper respiratory tract infections, pneumonia, etc., leading to the patient’s fever symptoms, which may lead to generalized chills. It is recommended that one should choose to seek medical attention to identify the cause in conjunction with one’s own condition.