Causes of elevated total cholesterol include: i. Consumption of foods with excessive cholesterol content, such as fatty meats, offal, cream, egg yolks, and fish roe can lead to elevated blood cholesterol levels. Second, long-term smoking, lack of exercise and weight gain can also lead to elevated cholesterol. The liver is the main organ for cholesterol synthesis and metabolism, and liver lesions can also lead to elevated cholesterol. Diseases can cause secondary elevation of cholesterol, such as hypothyroidism, diabetes and nephrotic syndrome. V. Genetic factors can also lead to familial hypercholesterolemia. Patients with elevated cholesterol need a low-fat diet to treat diseases that cause secondary elevation of cholesterol, and use oral statins to lower blood lipids and effectively reduce cholesterol levels.