Wiping the paper with blood may be perianal skin breakage and other uncontrollable factors; can also be the symptoms of certain diseases, such as hemorrhoids, anal fissure, etc., should be timely consultation to find out the cause of the disease. 1. Perianal skin breakage: may be by the quality of the toilet paper is too hard or use too much strength, resulting in perianal skin by friction rupture bleeding, generally this situation is less bleeding, pain is not strong, can be relieved on their own, do not have to worry about it too much. 2. Hemorrhoids: patients can be asymptomatic, but can also show bleeding, perianal itching, pain and other symptoms. 3. Anal fissure: it is the rupture or tearing of the skin of the anal canal and the formation of small ulcers. Can be caused by constipation or repeated diarrhea and other factors caused by the anal canal damage caused by the symptoms can be manifested as anal pain, blood on the toilet paper and so on. If there is blood on the wipes after stool, it may also be caused by the rectal anal mucous membrane tearing due to constipation, and may also be caused by rectal polyps, rectal tumor surface mucous membrane damage. Therefore, the discovery of blood after wiping paper, you should go to the hospital in time to consult the hospital related examination, in order to clarify the cause of the disease, and actively cooperate with the doctor’s treatment.