There are four specific symptoms of bladder cancer in late stage as follows: 1. Hematuria: hematuria is the most common symptom of bladder cancer. Data show that those who take this as the main symptom account for 94%. Hematuria is mostly microscopic hematuria, followed by microscopic hematuria. It can be intermittent, or complete hematuria, or terminal hematuria. Because of the diversity of hematuria, it is easy to be misdiagnosed or delayed diagnosis. If the disease develops or the scope of lesion is large or combined with infection, it can be combined with urinary tract irritation symptoms, discharge putrefactive material, discharge lumps, blood clots, or due to the obstruction of the urinary tract by lumps, urinary difficulty, dribbling down, or even urinary retention. 2.Urinary tract irritation symptom: The symptom may appear when the tumor occurs in the bladder triangle or combined with infection, or the symptom may be dominated by the symptom. It is reported that bladder irritation symptom also reveals the possibility of carcinoma in situ of bladder, so patients with bladder irritation symptom who lack sufficient basis of infection should be examined comprehensively as soon as possible to exclude bladder cancer. 3.Oedema:the legs are swollen, the stomach has ascites, and now there is incontinence of stool, yellow urine, yellow loose stool, and accompanied by a large amount of colorless, tasteless and transparent liquid, and it is often the case that the tumor alone produces this kind of colorless, tasteless and transparent liquid. 4.Other: if tumor infiltrates into ureteral orifice or grows in ureteral orifice, it can cause ureteral dilatation, which will lead to formation of hydronephrosis and increase in kidney size. When bladder cancer has lung, liver and bone metastasis, corresponding symptoms will appear, such as cough, shortness of breath, abnormal liver function, pain in liver area, bone pain in a certain place, and systematic examination should be carried out in order to make diagnosis in time and treat it as early as possible. There are many symptoms in advanced stage of bladder cancer, for which palliative surgery, chemotherapy and traditional Chinese medicine are the main treatments to alleviate the symptoms and improve the quality of life of patients, palliative surgery and chemotherapy are the main treatments for patients with advanced stage of bladder cancer. It is worth noting that when metastasis occurs, it increases the difficulty of treatment greatly. Patients with advanced bladder cancer should not give up the treatment, when metastasis occurs, there will be more symptoms, patients will suffer more, and the difficulty of treatment will be greater. Therefore, they should actively cooperate with the treatment and have regular review so as not to miss the condition.