Rheumatoid arthritis and rheumatoid arthritis differ in their etiology, clinical manifestations, laboratory tests and treatment. 1. Etiology: Rheumatoid arthritis is often associated with autoimmune reactions, infections (viruses or Streptococcus A, etc.) and genetic factors; rheumatoid arthritis is mainly a systemic allergic disease caused by hemolytic streptococcus. 2. Clinical manifestations: rheumatoid arthritis is mostly recurrent, symmetric, multiple small arthritis, morning stiffness can last more than 1 hour, accompanied by joint deformity (fingers can be swan-neck-like degeneration); rheumatoid arthritis is often red, swollen, hot, painful and multiple joints with wandering pain, which can be subsided after a few days. 3. Laboratory tests: rheumatoid arthritis can be seen as accelerated blood sedimentation, increased C-reactive protein, increased serum IgG, IgA, IgM, and positive rheumatoid factor; rheumatoid arthritis can be seen as accelerated blood sedimentation, increased anti-O titer, but negative rheumatoid factor. 4. Treatment: rheumatoid arthritis can take non-steroidal anti-inflammatory drugs (indomethacin, etc.), prednisone and other glucocorticoids and other drugs; rheumatoid arthritis commonly used antibiotics (penicillin, etc.) to clear streptococcal infection and non-steroidal anti-inflammatory drugs (indomethacin, etc.) analgesic treatment. All of the above drugs need to be used under the guidance of a doctor, it is recommended that patients are advised to regular hospitals rheumatology and immunology departments and other related departments for detailed consultation, standardized treatment in accordance with the doctor’s instructions.