1. Significant intraoperative bleeding and postoperative bleeding due to thrombocytopenia, lack of coagulation factors, prolonged bleeding time, etc. 2.Prolonged blood oozing time in the tissues after surgery due to abnormal coagulation function, thus aggravating the swelling in the surgical area, which may lead to the formation of local hematoma in severe cases, and may lead to respiratory difficulty or even asphyxia if the hematoma occurs in the floor of the mouth, parapharynx, submandibular space, etc. 3. Due to the decrease of hemoglobin, the healing speed of the wound is affected, resulting in delayed healing of the wound. 4. The combination of reduced leukocytes and poor body resistance, combined with the slow healing rate of the wound and the bacterial environment of the oral cavity in such patients, can lead to a higher probability of infection after tooth extraction. 5. Intraoperative hypoxia can be caused in patients with severe anemia due to the decrease of hemoglobin and various adverse stimuli during the operation. 6. There are interactions between some drugs used before and after tooth extraction and drugs used for the treatment of hematological diseases, such as: (1) Loxoprofen sodium capsules can enhance the anticoagulant effect of coumarin anticoagulant drugs (warfarin, etc.); (2) Ornidazole can inhibit the metabolism of anticoagulant warfarin, prolonging its half-life and enhancing its efficacy; (3) Glucocorticoids such as dexamethasone may affect the anticoagulant effect of coumarin anticoagulant drugs. (3) Glucocorticoids such as dexamethasone may affect the anticoagulant effect of coumarins. 7. Some antibacterial, analgesic and local anesthetic drugs used before and after tooth extraction may induce or aggravate hematologic diseases, such as: loxoprofen sodium capsule may cause hemolytic anemia; lincosamide antibacterial drugs such as lincomycin may occasionally cause leukopenia, neutropenia or lack of neutrophils, thrombocytopenia, etc.