You should never drink coffee during a cold. Coffee contains more caffeine, which will stimulate the human cerebral cortex and produce a feeling of excitement, thus making the patient sleepless. Patients with colds should rest more, and if you drink coffee during a cold, it is not conducive to rest, which is also very bad for recovery from the cold. In addition, coffee and cold medicine will also play a chemical reaction, especially drugs containing ephedrine, which has the effect of stimulating nerve excitement, if you drink coffee, the effect will be greatly enhanced, there will be symptoms of overdose. Cold medicines containing ephedrine are also relatively common, such as Sensachem, Contac. Antipyretic and analgesic cold medicine and central excitatory cold medicine, for the gastric mucosa was a great sense of irritation, especially the central excitatory drugs, containing a lot of caffeine, if taken after drinking coffee, will further increase the stimulation of the gastric mucosa, causing the phenomenon of stomach pain.