If you have hand, foot and mouth disease, after the blister breaks, you should promptly carry out local disinfection treatment, you can first wash with light salt water to keep the local skin clean, you can also disinfect with iodophor, de-iodize with alcohol, and cover with sterile gauze, which can well prevent the emergence of infection. During this period, you should pay attention to not let the baby touch the wound site with your hands as much as possible, because it is likely to itch during the wound recovery period. If contacted, it is likely to lead to an increased chance of infection. Attention should also be paid to improving the situation in many ways, for example, oral anti-inflammatory drugs can be taken to prevent infection. If symptoms persist without relief, antiviral treatment should be administered in a timely manner, and only when HFMD is completely cured can the skin infection be completely relieved. If there is a large area of infection during this period, it is also necessary to go to the hospital for systematic treatment in a timely manner.