Acute urticaria can be treated with antihistamines, glucocorticosteroids, vitamins and calcium. Acute urticaria is due to allergic causes, medication must be accompanied by avoidance of re-exposure to allergens. 1. Antihistamine drugs: such as levocetirizine hydrochloride tablets, levodiclovir tablets, chlorpheniramine maleate tablets and other anti-allergy drugs, is the first choice of drugs for the treatment of acute urticaria, according to the dose of the application of medical advice. 2. Glucocorticoid drugs: such as prednisone acetate tablets, betamethasone tablets, etc. Glucocorticoid drugs have anti-inflammatory, anti-allergic, anti-shock effect, suitable for more serious acute urticaria. 3. Vitamins and calcium drugs: usually can choose vitamin C tablets, calcium gluconate, can reduce capillary permeability, acute urticaria can play an auxiliary therapeutic role. Patients need to go to the regular hospital dermatology consultation, by the physician according to the condition of the treatment, they can not randomly use drugs.