Teenagers are susceptible to osteosarcoma, which is usually more common around the ages of 10 to 15, with a slightly higher percentage in boys. Many factors may predispose to osteosarcoma. If there is a family history of tumors, the chances of developing osteosarcoma increase. Osteosarcoma may be induced if there is regular exposure to chemicals or ionizing radiation, as in the case of non-osteosarcoma cancer patients undergoing radiation therapy. Viral infections and hormonal abnormalities may induce osteosarcoma. Osteosarcoma may form if fractures are not treated effectively and interfere with normal bone development. If there is pain in the bones and joints or lumps near the bones without a history of obvious trauma, or if unexplained bone injuries or fractures are detected, the possibility of osteosarcoma should be considered, and timely consultation should be made so that the doctor can clarify the cause of the disease and give targeted treatment.