The causes of wasting in diabetic patients include the following: a. High blood sugar, when the blood sugar of diabetic patients rises significantly, a large amount of glucose is excreted in the urine, and the body has fewer carbohydrates available for use, and can only carry out fat decomposition to supply energy. Therefore, patients will have the typical “three more and one less” symptoms of diabetes, resulting in significant weight loss. Insulin is not only a hypoglycemic hormone, but also a pro-synthetic hormone, which can promote the synthesis of protein, fat and glycogen. When the patient’s insulin deficiency is serious, there will be insufficient synthesis of protein, sugar and fat and enhanced catabolism, which will aggravate the degree of wasting. Third, diabetes diet control is too strict, when the diabetic patient’s diet control is too strict or biased, also easy to lead to wasting. Fourth, certain drugs, such as biguanide preparations may promote weight loss in diabetic patients. Fifth, other, if a diabetic patient is also combined with hyperthyroidism, malignant tumor and other wasting diseases, it may also easily lead to weight loss.