Colds do not usually cause tight cheeks. Colds are essentially acute upper respiratory tract infections that can be caused by viral or bacterial infections. The main clinical manifestations include nasal congestion, runny nose, sore throat, generalized muscle aches and pains, and fever, which do not cause tight cheeks. The area we often refer to as the cheek area is mainly the parotid gland, the biting muscle, its surrounding fat and skin, etc. There are many reasons for tightness in this area. There are many reasons for tightness in this area. It may be a pre-symptom of herpes zoster; lymphadenitis of the submandibular gland caused by viral or bacterial infections may also cause tightness in the cheeks; and in mumps, the parotid glands on both sides are swollen and painful, which can also cause tightness in the cheeks. It is recommended to go to the hospital in time for early and regular treatment when parotid tightness occurs.