The enterohepatic circulation refers to the drug passing through the liver, after metabolism by the liver, its metabolites or prototypes that have not been metabolized will be discharged into the duodenum through the bile, and then from the duodenum to the small intestine, part of it will be discharged, part of it will be reabsorbed through the small intestine, and the metabolites after reabsorption by the small intestine will flow into the liver through the hepatic portal vein, and then enter the intestinal cavity through the metabolism of the liver, so that the repeated process is called enterohepatic circulation. The process is called enterohepatic circulation. The enterohepatic circulation refers to one of the pathways of drug metabolism. If the enterohepatic circulation is inhibited, the metabolism of drugs will be accelerated, and if the enterohepatic circulation is not inhibited, the metabolism of drugs will be slowed down.