Degenerative osteoarthritis treatment may include non-steroidal anti-inflammatory drugs (e.g., ibuprofen, etc.) and dextrose, which can relieve most bone and joint pain and other symptoms. Degenerative arthritis is a chronic disease that damages the cartilage and tissues around the joints and usually cannot be reversed, but treatment can reduce pain and improve quality of life. Degenerative arthritis medication focuses on using medications that can help relieve arthritis symptoms (mainly pain). 1. Over-the-counter NSAIDs taken orally at recommended doses, such as ibuprofen and celecoxib, usually relieve osteoarthritis pain. However, oral NSAIDs can cause stomach upset, bleeding problems, and liver and kidney damage. NSAIDs can also be placed on the skin of affected joints in the form of gels or patches, such as flurbiprofen gel patches, which have fewer side effects and can also provide pain relief. 2. Oral administration of glucosamine can repair and protect damaged joint cartilage and slow down the process of degenerative osteoarthritis, and can be used as a nutritional supplement for osteoarthritis. 3. Sodium vitrate injected into the joint cavity can lubricate the joints to relieve pain, but some patients may not be effective. For the treatment of degenerative osteoarthritis and the use of medication, it is recommended to go to the orthopedic department of the hospital for a comprehensive evaluation and treatment as prescribed by the doctor.