High TSH may cause symptoms of hypothyroidism or subclinical hypothyroidism, such as chills, fatigue, alopecia, indifference, bradycardia, mucous edema, etc. Hyperthyroidism can also be caused by pituitary tumors, or there are no obvious symptoms. 1. Hypothyroidism: high TSH accompanied by low T3 and T4, clinical hypothyroidism, hypometabolic syndrome, chills, fatigue, alopecia, indifference, slow reaction, slow heart rate, severe mucous edema, and even pericardial effusion, etc., and need to take levothyroxine sodium tablets for treatment. 2. Subclinical hypothyroidism: TSH is high, T3 and T4 are in the normal range, which belongs to subclinical hypothyroidism, and there may be symptoms of hypothyroidism, or the symptoms are atypical, and there are only reduced physical strength and hyperlipidemia, and there may be no obvious clinical manifestations. 3. High TSH caused by pituitary tumor: it may show the symptoms of tumor compression or abnormal thyroid function, such as hyperthyroidism, fear of heat and sweating, easy to eat and easy to starve, weight loss, etc., which needs surgical treatment. When tsh thyroid stimulating hormone is high, you should go to regular hospitals and under the guidance of specialists for examination, clear diagnosis and cause-specific treatment, so as not to be negligent and careless, so as not to delay or aggravate the condition.