The treatment of terminal ileal ulcers is complicated, mainly including the following aspects: 1, to clarify the cause, generally considered to be caused by Crohn’s disease, intestinal tuberculosis, or intestinal leukoaraiosis, intestinal lymphoma and other diseases, pathological results are very critical, may have to do the examination, not in one step, to follow up and review. When the clinical diagnosis is not very clear, treatment should be carried out while observing; 2. A light diet should be the main focus, keep a happy mood, avoid straining or excessive stress; 3. Intestinal flora regulating drugs can be used, follow up well, and timely review of endoscopy; 4. After the diagnosis is clear, treatment should be carried out according to the respective treatment plan, such as Crohn’s disease can be treated with 5-aminosalicylic acid, hormones, immunosuppressants, antibiotics and For example, Crohn’s disease can be treated with 5-aminosalicylic acid, hormones, immunosuppressive agents, antibiotics and biological agents, and surgery if necessary. In the case of intestinal tuberculosis, treatment should be carried out according to the principles of intestinal tuberculosis treatment. In the case of intestinal lymphoma, treatment may require assistance from a hematologist. Intestinal leukoencephalopathy is an autoimmune disease and may require treatment under the guidance of the rheumatology department.