Crying after the 13-valent vaccine may be due to the emergence of localized redness, swelling, pain, hard nodules, etc., you can carry out localized hot compresses and other physical therapy methods, parents should calm the child’s emotions to ease the crying. 1. Localized redness and swelling: after the 13-valent vaccination, the local stimulation, there will be the phenomenon of redness and swelling, the baby will appear localized pain, appear continuous crying. It is necessary to promptly inspect the child’s vaccination site to determine the cause of the disease, and then apply localized hot compresses to promote blood circulation and alleviate the symptoms; 2. Pain: the injection process will cause arm pain, the child’s pain threshold is low, so it will cry, parents should calm the child’s emotions. 3. hard knot: during the injection, the nerves will be unconsciously tensed, this situation will affect the efficiency of the vaccine absorption, thus causing localized hard knots, which will cause swelling or distension, which will also cause the child to cry, the child should be allowed to keep the muscles relaxed, do not carry out heavy physical activities. In addition, parents should be reminded that frequent crying after 13-valent vaccine may not be a side effect of the vaccine. It is also important to strengthen the post-vaccination care of children, closely observe the changes in their vital signs, and consult a doctor immediately if there is any abnormality.