Starting from the Five Elements theory, we understand the characteristics of spleen and stomach diseases in Guangdong, and analyze the methods of regulating spleen and stomach diseases under the Five Elements Control Theory: strengthening the spleen mainly and regulating the qi; regulating the heart, liver, lungs and kidneys to promote the recovery of spleen and stomach functions. Spleen and stomach diseases are the most common and frequent disease system in modern clinical practice. Guangdong Province is a region with a high prevalence of spleen and stomach diseases due to its geographical location and special factors such as dietary habits, and ancestral medicine analyzes patients comprehensively from the five elements theory and treats them with evidence to achieve the effect of overall regulation. Guangdong Province is located in the southern subtropical coastal region, with humid weather, low air pressure, and a changeable climate, the natural climate is hot and humid, with cold and dampness predominating; the spleen and earth are easily trapped and gather dampness and produce phlegm, i.e., the spleen produces dampness; water and dampness in turn trap the spleen, i.e., dampness traps the spleen; local residents like to eat seafood, which is cold in nature and easily damages the spleen and stomach yang qi, resulting in spleen qi deficiency; therefore, Guangdong’s spleen and stomach diseases are characterized by a mixture of deficiency and reality. Spleen deficiency and phlegm-dampness are seen in each other, mostly in the form of spleen and stomach yin deficiency and spleen and stomach warmth. The relationship between the five elements: the five elements are the combination of the relationship between the five elements and the five elements, and the two elements are inseparable. There must be birth with grams and birth with grams. The Five Elements doctrine uses the five elements to produce and control each other to explain the relationship between the five organs that are both mutually supportive and mutually restrictive. Each of the five organs has a physiological connection between me and me, and me and me. The production and restraint of the five viscera explains that the function of each organ is not deficient due to the support of other organs, and not excessive due to the restraint and restraint of other organs; if the Qi of the organ is too strong, it is restrained by the Qi of other organs; if the Qi of the organ is deficient, it can be supplemented by the Qi of other organs. For example, if the Qi of the Spleen (Earth) is deficient, the Heart (Fire) will produce it; if it is excessive, the Liver (Wood) will restrain it. This relationship links the five organs into a whole and ensures the unity of the human internal environment. According to the theory of the five elements to regulate gastrointestinal diseases 1, Chinese medicine Tibetan elephant theory: the spleen is the main transport, spleen will transform the diet into water and grain essence, and its absorption, transfer to the viscera, nutrition and nourishment of the whole body, and excess water through the lungs and kidneys out of the body; spleen is the main blood, spleen regulates, control the normal operation of blood in the veins and does not escape from the veins; spleen is the main ascending, upward movement to maintain the transport of water and grain essence and the relative stability of the position of the internal organs. The spleen likes to dryness and hate dampness; the stomach is the main receiver of ripening water and grain, the stomach descends to maintain the smoothness of the gastrointestinal tract, the stomach likes to moisten and hate dryness; the spleen and stomach are the source of biochemistry of qi and blood, the root of the latter. 2, in the five elements theory: spleen and stomach is earth, from the properties of the five elements, the earth loves harvest, the earth has the characteristics of carrying things, biochemical, so called the earth carries four elements, the mother of all things, the earth has the meaning of birth, for the survival of all things in nature and human beings; five organs is a whole, when the spleen and stomach loss of health, spleen and stomach weakness, will cause other internal organs dysfunction; other internal organs dysfunction, can also cause the spleen and stomach dysfunction.