The obstruction of food passage in the stomach is due to lesions such as ulcers or cancerous tumors. It can be divided into two main categories: incomplete obstruction and complete obstruction. Pyloric obstruction is one of the common complications of gastric and duodenal ulcers and can occur in the recent (i.e., active) or late stage of ulcer disease. The following diseases are also causes of food passage obstruction in the stomach: 1. duodenal smooth muscle sarcoma duodenal smooth muscle sarcoma is a myxoid tumor originating from the muscular layer or intrinsic muscular layer of the duodenal mucosa, or the vascular wall of the intestinal wall, and is classified into smooth muscle tumor (leiomyoma), smooth muscle sarcoma (leiomyosarcoma), and epithelioid smooth muscle tumor ( leiomyoblastoma), the latter being rare. The latter is rare, while smooth muscle tumor and smooth muscle sarcoma show no significant difference, and it is difficult to distinguish their nature in general view, so they are often discussed together clinically. 2. Congenital duodenal atresia Congenital duodenal atresia is a disorder of intestinal development caused by incomplete vacuolization of the intestinal canal during the embryonic period. The disease was first described by Calder in 1733, but it was not until 1916 that the first surgical treatment was performed on an infant with this disease. The surgical method used by Ladd and Gross in 1941 was confirmed and is still used today. Congenital stenosis of duodenum is similar to duodenal atresia, except that the degree of developmental abnormality during the embryonic period is less severe and only stays at the stenosis stage, so the prognosis is better. The morbidity rate is also lower. 4, gastric ulcer Gastric ulcer is a kind of peptic ulcer, that is, chronic ulcer occurring in the stomach and duodenum, is a multi-morbid and common disease. There are various factors in the formation of ulcers, among which the digestive effect of acidic gastric juice on the mucosa is the basic factor in the formation of ulcers. The majority of ulcers occur in the duodenum and stomach in any part of the body exposed to acidic gastric juices, such as the lower esophagus, the anastomosis after gastrointestinal anastomosis, the jejunum, and Meckel’s diverticulum with ectopic gastric mucosa, so it is also called gastric/duodenal ulcer. Among them, delayed gastric emptying and bile reflux, abnormal action of gastrointestinal peptides, genetic factors, pharmacological factors (such as aspirin, many anti-inflammatory painkillers, etc.), environmental factors and psychological factors are associated with the development of gastric ulcers. The main manifestations are, hidden pain, dull pain, distension, burning pain or hunger-like pain in the upper abdomen. About 10% of the population has suffered from peptic ulcer in their lifetime, and the disease can be seen at any age, with the majority being 20-50 years old and more men than women.