There is no fastest cure for pemphigus. General treatment, medication and other treatments need to be given according to the severity of the patient’s condition, activity level and classification of pemphigus. 1. General treatment: during the treatment period, patients should strengthen the supportive therapy, eat a light diet, eat more nutritious and easy-to-digest food, so as to prevent hypoproteinemia, and at the same time, correct the disturbance of water and electrolyte balance in time. At the same time, we need to take care of the skin and mucous membrane to prevent infection. 2. Drug therapy: glucocorticoids are the first-line drugs for the treatment of pemphigus vulgaris, and the specific method and dosage should be decided according to the patient’s lesion range, severity, activity and other factors. Long-term application of glucocorticoids may cause diabetes, hypertension, osteoporosis and other adverse reactions. In addition, it is possible to combine the treatment with immunosuppressants (such as morphimecoxib, methotrexate, etc.) and biological agents (such as rituximab, etc.). These drugs are contraindicated in patients with severe infections. 3. Other treatments: For other types of pemphigus, such as paraneoplastic pemphigus, surgery or radiotherapy can be used to treat the primary tumor. It is recommended that patients suffering from pemphigus should consult a doctor in time and take standardized methods of treatment under the doctor’s guidance. It is recommended to use medication under the guidance of the doctor, do not blindly self-medication.