Urinary bile 4 + suggests that the increase in urinary bile, may be related to hemolytic jaundice, acute hepatitis, kidney lesions and other diseases, belong to a more serious situation, need to clarify the cause of the disease in time, early treatment, otherwise the disease will further develop and threaten the patient’s life. 1. Hemolytic jaundice: after hemolysis occurs in the body, red blood cells are destroyed, leading to an increase in bilirubin in the blood, which is processed in the liver and then transported to the intestines to be broken down by bacteria into urobilinogen to increase the amount of urobilinogen partially absorbed by the intestinal wall to return to the bloodstream through the kidneys and increase the amount of discharged. If not treated in time, hemolysis will lead to anemia, elevated bilirubin value in the body, affecting the function of systemic organs and even death due to systemic organ failure. 2. Acute hepatitis: Acute hepatitis leads to destruction of liver cells, causing hepatocellular jaundice, causing increased urobilinogen. Acute hepatitis easily leads to rapid necrosis of liver cells, and there is a tendency of liver failure if not treated in time. 3. Renal lesions: renal lesions can lead to increased permeability of the renal filtration membrane, increased urobilinogen filtration, resulting in increased urobilinogen test value. Failure to treat renal lesions in a timely manner will lead to continued development of renal lesions, even to the stage of renal failure. Therefore, urobilinogen 4+ should go to the hospital in time, improve the examination, clarify the cause of elevated urobilinogen, and timely treatment.