The swollen piece on the leg of the organism is hard and painful, which is considered to be caused by the following reasons: 1. Consider that the swollen piece on the leg is caused by the formation of venous thrombosis of the organism. Venous thrombosis is mostly caused by poor venous blood circulation or long-term varicose veins in the body, resulting in thrombosis, swelling and pain in the legs. For this kind of swollen leg and pain, it is necessary to go to the vascular surgery department of the hospital and do vascular ultrasound examination of the lower limbs to clarify, if it is diagnosed as deep vein thrombosis of the lower limbs, it is necessary to place a filter and apply thrombolytic therapy. 2. Consider that the pain is caused by strain and strain of the calf muscles and soft tissues due to the recent overly strenuous activities or trauma. For the pain caused by this condition, on the one hand, it needs rest; on the other hand, it can be treated with the application of blood-stasis activating, anti-swelling and pain-relieving drugs, including topical application of Fotarine, etc.