Weak positive fecal occult blood can be caused by aspirin and other drug factors, but also by acute gastroenteritis, gastric cancer and other pathological factors. 1. Drug factors: such as aspirin, warfarin and other anticoagulant drugs, if taken for a long time may lead to gastric mucous membrane damage, resulting in gastrointestinal bleeding, black stools, tarry stools and other symptoms, and fecal occult blood test is weakly positive. After stopping the drug for a period of time, the above symptoms can gradually return to normal. 2. Pathologic factors: (1) Inflammatory diseases: such as acute gastroenteritis, gastric and duodenal ulcer, ulcerative colitis, etc., all caused by inflammation stimulation of the gastrointestinal mucosa causing gastrointestinal bleeding symptoms, may also be accompanied by abdominal pain, abdominal distension, diarrhea, nausea, vomiting and other symptoms, and fecal occult blood test weak positive. (2) Neoplastic diseases: such as gastric cancer, intestinal cancer, etc., due to the invasion of tumor cells into the mucosa of gastrointestinal tract, it can cause gastrointestinal bleeding, i.e., weakly positive fecal occult blood test, and may be accompanied by systemic symptoms, such as weight loss, fever, malaise, anemia and so on. Weakly positive fecal occult blood test is recommended to consult a doctor in time for a clear diagnosis and targeted treatment under the doctor’s guidance.