Pre-macular membrane is a fibrous membrane that grows along the surface of the macula within the retina. 6.4% of people over 50 years old can see pre-macular membrane, of which about 20% in both eyes. It can cause distortion and edema of the retina in the macular area, resulting in distortion, enlargement of visual objects and loss of visual acuity. In mild cases, it only shows enhanced reflection on the retinal surface, like a layer of cellophane; in severe cases, translucent film or opaque grayish film can be seen in front of the macular retina, accompanied by macular folds, vascular tortuosity, macular displacement, and occasionally retinal hemorrhage. Fundus fluorescence angiography (FA) examines the retinal vascular tortuosity in the macula and converges toward the center of the macula, and in more severe cases, fluorescence leakage and macular dye accumulation can be seen. Optical coherence tomography (OCT) shows uneven signal enhancement of the retinal surface membrane tissue in the macula, and different degrees of macular tissue thickening with edema. The cause of the disease is unknown, and treatment and prognosis Most of the macular preretinal membranes show a layer of vitreous paper-like, without symptoms of visual changes, and can be observed. Progressive or severe loss of vision, visual distortion and macular edema can be treated by vitreous surgery to remove the macular pre-macular tissue. The surgery of macular anterior membrane is relatively simple in vitrectomy, generally in about 40 minutes to 1 hour About 70% to 80% of patients can improve their vision by more than 2 lines after macular anterior membrane peeling surgery, but some macular edema is slow to subside. Complications of surgical treatment are relatively rare and include cataract exacerbation, retinal fissures and retinal detachment.