Triple-negative breast cancer with BRCA-2 gene mutation should be diagnosed as soon as possible and actively treated, and the treatment means include surgery, chemotherapy, radiotherapy and other drugs. 1. Surgery: Surgery is one of the most commonly used methods, and it is the main treatment for breast cancer that has not yet developed distant metastasis. Surgery includes breast-conserving surgery, total mastectomy and prophylactic contralateral mastectomy (generally not recommended). 2. Chemotherapy: it is one of the commonly used treatments for triple-negative breast cancer. Commonly used chemotherapy drugs include paclitaxel, epirubicin, gemcitabine, cisplatin and so on. 3. Radiotherapy: including intraoperative radiotherapy and postoperative adjuvant radiotherapy. 4. Other drugs, such as immunotherapy drugs PD-1 and PD-L1. Patients with triple-negative breast cancer with BRCA-2 gene mutation should consult the doctor as early as possible and under the guidance of oncologists for standardized treatment to avoid delay.