Typical clinical symptoms of uremia mainly include early systemic symptoms, urinary system symptoms, gastrointestinal symptoms, hematologic symptoms, cardiovascular system symptoms, respiratory system symptoms and so on. 1. Early systemic symptoms: mainly manifested as poor spirit, poor appetite, fatigue, weight loss or weight gain. 2. Urinary system symptoms: they may manifest as lumbago, increased nocturia and other symptoms. 3. Gastrointestinal symptoms: mainly manifested as nausea, vomiting, diarrhea, gastrointestinal bleeding, water-electrolyte balance disorder. 4. Hematological symptoms: some patients may have anemia and abnormal white blood cells. 5. Cardiovascular system symptoms: angina pectoris, exertional dyspnea, arrhythmia, hypertension and other symptoms may occur. In severe cases, sudden death may occur. 6. Respiratory system symptoms: mainly manifested as shortness of breath, shortness of breath, pleurisy, pulmonary edema, pleural effusion and other discomforts. In addition, uremia may also appear other symptoms, such as insomnia, inattention, bone mineral metabolism disorders, skin itching and other discomforts. It is recommended that patients with uremia seek timely medical treatment, complete relevant examinations under the guidance of the doctor, and actively cooperate with the doctor to standardize the treatment.