There are many differences between obesity-associated nephropathy and nephritis, such as etiology, clinical manifestations, treatment and so on.
1. Etiology: obesity-related nephropathy is related to obesity, and the severity of the disease is related to the degree of obesity. Nephritis is divided into acute and chronic, acute nephritis is related to bacterial and other microbial infections; chronic nephritis starts with immune-mediated inflammation.
2. Clinical manifestations: obesity-related nephropathy has an insidious onset, and patients have no obvious symptoms, which can be detected during the examination, mainly manifested as foamy urine, edema, renal function abnormality, etc. Most of the patients will be combined with one or more metabolic disorders, such as insulin resistance, hypertriglyceridemia, etc. The nephritis is characterized by proteinuria, hematuria, and blood pressure.
While nephritis is mainly characterized by proteinuria, hematuria, edema and hypertension, acute nephritis starts rapidly and progresses quickly, while chronic nephritis may have no obvious symptoms in the early stage, but the renal function may gradually deteriorate.
3. Treatment: The treatment principle of obesity-related nephropathy is mainly to control body weight, and for those with glucose metabolism disorder, metformin and insulin can be given as prescribed by doctors; for those with high blood pressure, captopril and chlorosartan can be used.
Acute nephritis generally supportive symptomatic treatment, there is obvious evidence of infection can be given penicillin and other antibiotic treatment; chronic nephritis treatment includes low-salt, low-fat, high-quality, low-protein diet, antihypertensive and lowered urinary protein therapy, immunosuppressive therapy, etc., the commonly used drugs include valacyclovir, enalapril, methylprednisolone, cyclophosphamide and so on.
Obesity-related nephropathy or nephritis patients should go to the hospital in time, under the guidance of professional physicians. Drugs should be used according to the doctor’s prescription, do not self-medicate.