Gastritis with enterocolitis is usually considered when the normal epithelial cells of the patient’s gastric mucosa are gradually replaced by epithelial cells of the intestinal mucosa. This condition requires regular review. With the progress of time, gastric mucosal enterosis can be gradually transformed into precancerous lesions, but for mild gastritis with enterosis, there is no need for special treatment, patients need to undergo gastroenteroscopy once every six months to clearly understand their own disease status. For moderate to severe enterocolitis, endoscopic treatment is needed to reduce the risk of cancer in combination with clinical manifestations. In addition, patients with gastritis with intestinal chemosis are recommended to improve the examination of Helicobacter pylori, and if there is, it is recommended to take four drugs for sterilization treatment, such as omeprazole, clarithromycin, amoxicillin, bismuth pectin, etc., and the specific drugs should be used in accordance with the doctor’s instructions. Gastritis with intestinalization can let go to the local hospital chemical internal medicine department, under the guidance of the doctor for examination and treatment.