Hard skin callus on the feet need to be treated according to the cause of the symptoms, common causes of callus, metatarsal warts, etc., usually using medication, physical therapy methods to eliminate. 1. callus: callus is due to long-term friction and pressure caused by the thickening of the skin stratum corneum, manifested in the skin surface appears flat or slightly thickened callus, touch hard. The callus can be flattened, local topical salicylic acid cream, urea cream, vitamin A ointment and other ointments to eliminate. 2. metatarsal warts: metatarsal warts is due to the human papilloma virus infection caused by the foot skin disease, manifested in the soles of the feet appeared small, shiny pimples, with the development of the disease gradually increase and keratinization, due to pressure and the formation of yellowish or tawny hard skin callus. Local topical salicylic acid cream and retinoic acid ointment can be used. Refractory plantar warts can be treated with intradermal injections, such as pingyangmycin injection. You can also use physical therapy methods, such as liquid nitrogen cryotherapy to eliminate. All of the above drugs need to be used under the guidance of a professional doctor, avoid self-medication. The hard skin callus on the feet may also have other causes, it is recommended to go to the hospital in time to improve the examination, clear the cause of the disease to give targeted treatment.