Adapalene Gel can be applied all over the face for patients with indications and under the guidance of a medical professional. Adapalene Gel is an anti-acne medication that is used to treat acne vulgaris, which is characterized by papules, pimples, and pustules, and can also be used for acne on the face and chest and back. It is contraindicated in pregnant women and those who are allergic to the composition of the drug Adapalene Gel. It is contraindicated in breastfeeding women. Adverse reactions such as scaling, itching, burning, dryness, etc. often occur at the site of application during the first 2-4 weeks of the medication period, but they are mostly mild or moderate, and should be reduced or discontinued if serious adverse reactions occur. Facial use of adapalene gel need to pay attention to avoid contact with the eyes, nasal mucosa, lips, inner canthus and other mucosal tissues, skin cuts, abrasions, eczema, acne, and sunburn, prohibit the use of the drug. It is prohibited to use with other vitamin A acid drugs at the same time. If the face suffers from acne and the area is large, can be used on the whole face under the guidance of a professional doctor, with the use of drugs need to be decided according to the condition, need to comply with medical advice.