Gallbladder polyp lesions are not uncommon clinically, and surgery is the radical cure, but not all gallbladder polyps require surgical treatment. However, not all gallbladder polyps require surgical treatment. The disease regression varies depending on the type and size of the lesion. Most gallbladder polyps are found during ultrasound examination and are asymptomatic. About 1-10% of patients with gallbladder polyps will develop cancer. A gallbladder polyp is a small bulge in the cavity of the gallbladder, and its formal scientific name should be gallbladder polyp-like lesion. Timing of surgery: It is sometimes difficult to determine the nature of gallbladder polyp-like lesions before surgery. According to the high risk factors for malignancy of gallbladder polyp-like lesions, we propose the following surgical indications: (1) Single lesion, larger than 10 mm, with a thick tip, especially if located in the neck of the gallbladder and older than 50 years of age. (2) Multiple lesions with gallbladder stones, symptomatic, and age >50 years. (3) Single lesion, less than 10 mm, asymptomatic, age less than 50 years, observation and follow-up are allowed; lesions that increase in size or change in morphology should be treated surgically. (4) Doppler ultrasound examination of the lesion with abundant blood supply suggests malignant neoplasm. (5) CEA (tumor marker), the measured value is significantly elevated and other gastrointestinal tumors are excluded. (6) Gallbladder polyp-like lesions with significant symptoms and recurrent recurrence. (7) Asymptomatic patients with diameter less than 5 mm should be followed up at intervals of 3 to 5 months. Once the lesion is enlarged or symptomatic, surgery should be performed.