OBJECTIVE: To investigate the method and feasibility of transumbilical single-port foreign body-free laparoscopic surgery. METHODS: Twenty-four patients with gallbladder disease and nine patients with acute appendicitis underwent transumbilical single-port foreign body-free laparoscopic cholecystectomy and appendectomy. RESULTS: All 33 operations were successful. The average operating time of laparoscopic cholecystectomy was 45 minutes and that of laparoscopic appendectomy was about 35 min. No drains were placed, and no complications such as bleeding and bile leakage occurred. Conclusion: Transumbilical single-port foreign body-free laparoscopic cholecystectomy is safe and feasible, with no obvious postoperative abdominal wall scars and satisfactory cosmetic results, but the operation is more difficult than conventional laparoscopic surgery.