Yellowish greasy discharge from the ears of newborns may be normal secretions, amniotic fluid deposits, or may be associated with inflammation of the external ear canal. It can be managed by general treatment, flushing of the external ear canal, and anti-inflammatory medication. 1. General treatment: If it is a normal secretion from the sebaceous glands or amniotic fluid deposits, it can provide a certain degree of protection to the external auditory canal of the newborn, and usually does not require special treatment. If the amniotic fluid is retained in the newborn’s ear during birth, a yellowish greasy secretion may form after precipitation, which is not a cause for concern, and can be gently wiped away with a baby cotton swab. 2. External ear canal rinsing: If the secretion is hard and dry due to long time without treatment, 5% sodium bicarbonate solution can be dropped into the ear canal first, and after it is softened, the external ear canal can be rinsed with saline, or cleaned up with the assistance of otoscope, to avoid damaging the external auditory canal and the tympanic membrane. 3. Anti-inflammatory drug treatment: if the child’s ear discharge has a foul odor, accompanied by flaking, itching, skin edema and other symptoms, it may be otitis externa. In this case, 2% acetic acid can be used to smear the external ear canal, and hydrocortisone butyrate cream can be applied to the affected area for 7 days for anti-infection treatment. When yellowish greasy secretions appear in the ears of newborns, parents should take their newborns to the doctor in time due to the low resistance of newborns, and avoid operating or using medication at home on their own, so as to avoid adverse effects. All of the above medications should be used in accordance with the doctor’s prescription.